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New Hope for Adhesive Arachnoiditis: Study Shows Deterioration Can Be Stopped


For years, a diagnosis of Adhesive Arachnoiditis (AA) has been met with a sense of hopelessness, often viewed as an untreatable disease destined for irreversible decline1111111. However, a groundbreaking final report from the Tennant Foundation, authored by Dr. Forest Tennant, offers a powerful message of hope: the deterioration of AA can be contained and controlled222.


This study delves into the reasons for clinical decline in AA patients and, more importantly, identifies the measures that can successfully stop or slow its progression3.



What is Adhesive Arachnoiditis (AA)?


At its core, AA is an inflammatory disease affecting the spinal tissues4. Inflammation occurs in two key areas simultaneously: the cauda equina nerve roots and the arachnoid membrane, which is the inner lining of the spinal canal's cover5. This inflammation creates sticky adhesions that glue these nerve roots together, forming microscopic masses6.


Dr. Tennant describes these masses as being like "boulders in a creek" that disrupt the flow of spinal fluid, which can lead to headaches, dizziness, and blurred vision7. These masses are also referred to as small "balls of fire," hot and painful, entrapping the nerves that connect to the legs, feet, bladder, bowel, and sexual organs8. This ongoing inflammatory process is the cause of the continuous and progressive deterioration seen in AA9.



The Hidden Driver: Autoimmunity and Epstein-Barr Virus (EBV)


A critical finding from the study is that the inflammation in AA is primarily caused by autoimmunity—a process where the body mistakenly attacks its own tissues10. The study overwhelmingly points to the Epstein-Barr Virus (EBV) as the main culprit11.


In the study of 45 participants with MRI-documented AA, the results were striking:

  • All 45 participants had elevated VCA antibodies, indicating past EBV reactivations12.


  • 44 out of 45 (97.8%) had elevated EBNA antibodies, suggesting the presence of autoimmunity13.


This autoimmune response is often triggered after the body undergoes severe biological stress, such as trauma, infection, a spinal medical procedure, or significant psychological stress14.



What Works? The 3-Component Protocol to Stop Deterioration


The study confirms the effectiveness of a three-component medical protocol designed to fight AA on all fronts15151515:



  1. Control Pain: Severe, intractable pain is a near-universal symptom of AA16.



  2. Suppress Inflammation and Autoimmunity: This component should have a special focus on managing Epstein-Barr Virus reactivation17.



  3. Regenerate Damaged Tissue: Assisting the body's natural healing processes18.


The most encouraging data comes from the 14 participants (31.1%) who reported their condition was stable, improving, or had stopped deteriorating19191919. A review of their treatment regimens revealed a common theme: a comprehensive approach.



  • Good Pain Control was Crucial: All 14 participants in this group had good enough pain control to function mentally and physically20202020. They all used either opioids or low-dose naltrexone21. In contrast, 4 of the 5 participants who were rapidly deteriorating reported poor pain control22222222.



  • Targeting Inflammation and EBV: All 14 participants who halted deterioration used one or more therapies to suppress inflammation and prevent EBV reactivation23. The most commonly used supplement was curcumin/turmeric24. Many also used corticosteroids, ketorolac, and antiviral agents25.



Do You Have the 7 Major Symptoms of AA?


The study also confirmed the validity of a seven-symptom screening test to help identify AA at an earlier stage26. In the study, 95.6% of participants reported having four or more of these seven symptoms27. If you experience several of the following, it may be worth discussing an MRI with your doctor28282828.


  1. Do you get sharp, stabbing pains in your lower back when you twist, turn, or bend? 29


  2. Do you experience bizarre skin sensations, like crawling insects or water dripping down your legs? 30


  3. Do you have burning pains in your feet and/or groin area? 31


  4. Does your pain temporarily lessen when you stand or recline? 32


  5. Do you have leg weakness and/or pain that radiates down one or both legs? 33


  6. Do you have any bladder dysfunction, such as dribbling or difficulty starting or stopping urination? 34


  7. Do you sometimes have a headache, dizziness, or blurred vision? 35



A New Outlook for AA Patients


This study, while small, is incredibly encouraging36. It powerfully refutes the old mantra that Adhesive Arachnoiditis is a hopeless, untreatable condition37. The evidence suggests that with a dedicated and comprehensive treatment plan focusing on pain control and suppressing EBV-driven autoimmunity, the progression of this debilitating disease can be contained38. For thousands of people living with AA, this report represents a significant and welcome step forward.


Here’s the link to download the report: Stopping the Deterioration of Adhesive Arachnoiditis by Dr. Forest Tennant:



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Good information. Some additional information is that I have a massage chair which I think improves CSF flow. I also advocate gentile chiropractic care, there is a table that many use called Intersegmental traction (IST) which is adjustable and also helps CSF flow. Some also have lasers which can target the affected area of adhesions. I think it helps.

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